Escitalopram for the prevention of peginterferon-&#945;2a-associated depression in hepatitis C virus-infected patients without previous psychiatric disease: a randomized trial.

Schaefer, Martin; Sarkar, Rahul; Knop, Viola; Effenberger, Susanne; Friebe, Astrid; Heinze, Loni; Spengler, Ulrich; Schlaepfer, Thomas; Reimer, Jens; Buggisch, Peter; Ockenga, Johann; Link, Ralph; Rentrop, Michael; Weidenbach, Hans; Fromm, Gwendolyn; Lieb, Klaus; Baumert, Thomas F; Heinz, Andreas; Discher, Thomas; Neumann, Konrad; Zeuzem, Stefan; Berg, Thomas

Escitalopram for the prevention of peginterferon-α2a-associated depression in hepatitis C virus-infected patients without previous psychiatric disease: a randomized trial.

Schaefer, Martin; Sarkar, Rahul; Knop, Viola; Effenberger, Susanne; Friebe, Astrid; Heinze, Loni; Spengler, Ulrich; Schlaepfer, Thomas; Reimer, Jens; Buggisch, Peter; Ockenga, Johann; Link, Ralph; Rentrop, Michael; Weidenbach, Hans; Fromm, Gwendolyn; Lieb, Klaus; Baumert, Thomas F; Heinz, Andreas; Discher, Thomas; Neumann, Konrad; Zeuzem, Stefan; Berg, Thomas.

Affiliation

Schaefer M; Department of Psychiatry, Psychotherapy and Addiction Medicine, Kliniken Essen-Mitte, Henricistr. 92, 45136 Essen, Germany. m.schaefer@kliniken-essen-mitte.de

Ann Intern Med ; 157(2): 94-103, 2012 Jul 17.

Article in En | MEDLINE | ID: mdl-22801672

Subject(s)

Antidepressive Agents, Second-Generation/therapeutic use; Antiviral Agents/adverse effects; Citalopram/therapeutic use; Depression/prevention & control; Hepatitis C, Chronic/drug therapy; Interferon-alpha/adverse effects; Adult; Aged; Antidepressive Agents, Second-Generation/adverse effects; Citalopram/adverse effects; Depression/chemically induced; Depressive Disorder, Major/chemically induced; Depressive Disorder, Major/prevention & control; Double-Blind Method; Female; Humans; Male; Middle Aged; Prospective Studies; Quality of Life; Risk Factors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Citalopram / Interferon-alpha / Antidepressive Agents, Second-Generation / Hepatitis C, Chronic / Depression Type of study: Clinical_trials / Etiology_studies / Guideline / Observational_studies / Risk_factors_studies Aspects: Patient_preference Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: En Journal: Ann Intern Med Year: 2012 Document type: Article Affiliation country: Germany Country of publication: United States

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