In-vitro validation of cytokine neutralizing antibodies by testing with ovine mononuclear splenocytes.

Chen, X; Threlkeld, S W; Cummings, E E; Sadowska, G B; Lim, Y-P; Padbury, J F; Sharma, S; Stonestreet, B S

Chen, X; Threlkeld, S W; Cummings, E E; Sadowska, G B; Lim, Y-P; Padbury, J F; Sharma, S; Stonestreet, B S.

Affiliation

Chen X; Department of Pediatrics, The Alpert Medical School of Brown University, Women and Infants Hospital of Rhode Island, 101 Dudley Street, Providence, RI 02905, USA.

J Comp Pathol ; 148(2-3): 252-8, 2013 Feb.

Article in En | MEDLINE | ID: mdl-22819013

Subject(s)

Antibodies, Neutralizing/pharmacology; Cytokines/immunology; Cytokines/metabolism; Spleen/drug effects; Spleen/metabolism; Animals; Antibodies, Neutralizing/immunology; Cells, Cultured; In Vitro Techniques; Inflammation/drug therapy; Inflammation/metabolism; Inflammation/veterinary; Interleukin-1beta/immunology; Interleukin-1beta/metabolism; Interleukin-6/immunology; Interleukin-6/metabolism; Models, Animal; NF-kappa B/metabolism; STAT3 Transcription Factor/metabolism; Sheep; Sheep Diseases/drug therapy; Sheep Diseases/metabolism; Spleen/cytology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spleen / Cytokines / Antibodies, Neutralizing Type of study: Prognostic_studies Limits: Animals Language: En Journal: J Comp Pathol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United kingdom

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