The role of the dopaminergic system in mood, motivation and cognition in Parkinson's disease: a double blind randomized placebo-controlled experimental challenge with pramipexole and methylphenidate.

Drijgers, Rosa L; Verhey, Frans R J; Tissingh, Gerrit; van Domburg, Peter H M F; Aalten, Pauline; Leentjens, Albert F G

Drijgers, Rosa L; Verhey, Frans R J; Tissingh, Gerrit; van Domburg, Peter H M F; Aalten, Pauline; Leentjens, Albert F G.

Affiliation

Drijgers RL; Department of Psychiatry, Maastricht University Medical Centre, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands.

J Neurol Sci ; 320(1-2): 121-6, 2012 Sep 15.

Article in En | MEDLINE | ID: mdl-22824349

Subject(s)

Affect/physiology; Benzothiazoles/pharmacology; Cognition/physiology; Dopaminergic Neurons/physiology; Methylphenidate/pharmacology; Motivation/physiology; Parkinson Disease/psychology; Affect/drug effects; Aged; Cognition/drug effects; Dopamine Agonists/pharmacology; Dopamine Uptake Inhibitors/pharmacology; Dopaminergic Neurons/drug effects; Double-Blind Method; Female; Humans; Male; Middle Aged; Motivation/drug effects; Pramipexole; Psychiatric Status Rating Scales/statistics & numerical data; Psychomotor Performance/drug effects; Psychomotor Performance/physiology; Reaction Time/drug effects; Reaction Time/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Parkinson Disease / Cognition / Affect / Benzothiazoles / Dopaminergic Neurons / Methylphenidate / Motivation Type of study: Clinical_trials Limits: Aged / Female / Humans / Male / Middle aged Language: En Journal: J Neurol Sci Year: 2012 Document type: Article Affiliation country: Netherlands

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