Influenza nucleoprotein: promising target for antiviral chemotherapy.

Cianci, Christopher; Gerritz, Samuel W; Deminie, Carol; Krystal, Mark

Cianci, Christopher; Gerritz, Samuel W; Deminie, Carol; Krystal, Mark.

Affiliation

Cianci C; Bristol-Myers Squibb Research and Development, Wallingford, CT, USA. christopher.cianci@bms.com.

Antivir Chem Chemother ; 23(3): 77-91, 2012 Jul 26.

Article in En | MEDLINE | ID: mdl-22837443

Subject(s)

Alphainfluenzavirus/drug effects; Antiviral Agents/pharmacology; Nucleoproteins/metabolism; Orthomyxoviridae Infections/drug therapy; Viral Proteins/metabolism; Amides/chemistry; Amides/pharmacology; Animals; Antiviral Agents/chemistry; Drug Discovery/methods; Humans; Influenza, Human/drug therapy; Influenza, Human/virology; Alphainfluenzavirus/metabolism; Models, Molecular; Molecular Targeted Therapy/methods; Nucleoproteins/chemistry; Orthomyxoviridae Infections/virology; Piperazines/chemistry; Piperazines/pharmacology; Viral Proteins/chemistry; Virus Replication/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Viral Proteins / Orthomyxoviridae Infections / Alphainfluenzavirus / Nucleoproteins Limits: Animals / Humans Language: En Journal: Antivir Chem Chemother Journal subject: QUIMICA / TERAPIA POR MEDICAMENTOS / VIROLOGIA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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