Your browser doesn't support javascript.
loading
Expression and function of APP and its metabolites outside the central nervous system.
Puig, Kendra L; Combs, Colin K.
Affiliation
  • Puig KL; Department of Pharmacology, Physiology and Therapeutics, University of North Dakota School of Medicine and Health Sciences, Grand Forks, ND 58203, USA.
Exp Gerontol ; 48(7): 608-11, 2013 Jul.
Article in En | MEDLINE | ID: mdl-22846461
ABSTRACT
Amyloid precursor protein (APP) derived amyloid beta (Aß) peptides have been extensively investigated in Alzheimer's disease pathology of the brain. However, the function of full length APP in the central nervous system remains unclear. Even less is known about the function of this ubiquitously expressed protein and its metabolites outside of the central nervous system. This review summarizes key aspects of the current understanding of the expression and function of APP and its proteolytic fragments in specific non-neuronal tissues.
Subject(s)
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Amyloid beta-Protein Precursor Limits: Animals / Humans Language: En Journal: Exp Gerontol Year: 2013 Document type: Article Affiliation country: United States
Fulltext
Add to My VHL
Print
XML
PubMed Links
Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Amyloid beta-Protein Precursor Limits: Animals / Humans Language: En Journal: Exp Gerontol Year: 2013 Document type: Article Affiliation country: United States