Methylene blue protects against TDP-43 and FUS neuronal toxicity in C. elegans and D. rerio.

Vaccaro, Alexandra; Patten, Shunmoogum A; Ciura, Sorana; Maios, Claudia; Therrien, Martine; Drapeau, Pierre; Kabashi, Edor; Parker, J Alex

Vaccaro, Alexandra; Patten, Shunmoogum A; Ciura, Sorana; Maios, Claudia; Therrien, Martine; Drapeau, Pierre; Kabashi, Edor; Parker, J Alex.

Affiliation

Vaccaro A; Université de Montréal Hospital Research Centre, Montréal, Québec, Canada.

PLoS One ; 7(7): e42117, 2012.

Article in En | MEDLINE | ID: mdl-22848727

Subject(s)

Caenorhabditis elegans/cytology; DNA-Binding Proteins/metabolism; Methylene Blue/pharmacology; Neurons/drug effects; Neuroprotective Agents/pharmacology; RNA-Binding Protein FUS/metabolism; Zebrafish/metabolism; Animals; Behavior, Animal/drug effects; Caenorhabditis elegans/drug effects; Caenorhabditis elegans/genetics; Caenorhabditis elegans/metabolism; DNA-Binding Proteins/genetics; Humans; Methylene Blue/administration & dosage; Motor Neurons/drug effects; Motor Neurons/metabolism; Mutation; Neurons/metabolism; Neuroprotective Agents/administration & dosage; Oxidative Stress/drug effects; Phenotype; RNA-Binding Protein FUS/genetics; Time Factors; Zebrafish/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Zebrafish / Caenorhabditis elegans / Neuroprotective Agents / RNA-Binding Protein FUS / DNA-Binding Proteins / Methylene Blue / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Canada

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