Reductive whole-cell biotransformation with Corynebacterium glutamicum: improvement of NADPH generation from glucose by a cyclized pentose phosphate pathway using pfkA and gapA deletion mutants.

Siedler, Solvej; Lindner, Steffen N; Bringer, Stephanie; Wendisch, Volker F; Bott, Michael

Siedler, Solvej; Lindner, Steffen N; Bringer, Stephanie; Wendisch, Volker F; Bott, Michael.

Affiliation

Siedler S; Institut für Bio-und Geowissenschaften, IBG-1: Biotechnologie, Forschungszentrum Jülich GmbH, 52425, Jülich, Germany.

Appl Microbiol Biotechnol ; 97(1): 143-52, 2013 Jan.

Article in En | MEDLINE | ID: mdl-22851018

Subject(s)

Acetoacetates/metabolism; Alcohol Dehydrogenase/metabolism; Corynebacterium glutamicum/metabolism; Glucose/metabolism; Hydroxybutyrates/metabolism; NADP/metabolism; Pentose Phosphate Pathway/genetics; Alcohol Dehydrogenase/genetics; Biotransformation; Corynebacterium glutamicum/genetics; Gene Deletion; Levilactobacillus brevis/enzymology; Levilactobacillus brevis/genetics; Metabolic Engineering; Plasmids; Recombinant Proteins/genetics; Recombinant Proteins/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pentose Phosphate Pathway / Alcohol Dehydrogenase / Corynebacterium glutamicum / Glucose / Hydroxybutyrates / NADP / Acetoacetates Language: En Journal: Appl Microbiol Biotechnol Year: 2013 Document type: Article Affiliation country: Germany

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