High-speed tracking of murine cardiac stem cells by harmonic nanodoublers.
Small
; 8(17): 2752-6, 2012 Sep 10.
Article
in En
| MEDLINE
| ID: mdl-22859385
ABSTRACT
Potassium niobate nonlinear nanoparticles are used for the first time to monitor the evolution of embryonic stem cells (ESC) by second harmonic microscopy. These particles feature the complete absence of photo-bleaching and unlimited excitation wavelength flexibility. The potential of this approach is made evident for tissue-regeneration studies and applications, by capturing a high-speed movie of ESC-derived cardiomyocytes autonomously beating within a cluster. Time-resolved data are analyzed to retrieve 3D information of the contraction pattern at the cellular level.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Nanotechnology
/
Embryonic Stem Cells
/
Myocardium
Limits:
Animals
Language:
En
Journal:
Small
Journal subject:
ENGENHARIA BIOMEDICA
Year:
2012
Document type:
Article
Affiliation country:
Switzerland