CD47(low) status on CD4 effectors is necessary for the contraction/resolution of the immune response in humans and mice.

Van, Vu Quang; Baba, Nobuyasu; Rubio, Manuel; Wakahara, Keiko; Panzini, Benoit; Richard, Carole; Soucy, Genevieve; Franchimont, Denis; Fortin, Genevieve; Torres, Ana Carolina Martinez; Cabon, Lauriane; Susin, Santos; Sarfati, Marika

Van, Vu Quang; Baba, Nobuyasu; Rubio, Manuel; Wakahara, Keiko; Panzini, Benoit; Richard, Carole; Soucy, Genevieve; Franchimont, Denis; Fortin, Genevieve; Torres, Ana Carolina Martinez; Cabon, Lauriane; Susin, Santos; Sarfati, Marika.

Affiliation

Van VQ; Immunoregulation Laboratory, Centre Hospitalier de l'Université de Montréal, Research Center (CRCHUM), Notre-Dame Hospital, Montreal, Quebec, Canada.

PLoS One ; 7(8): e41972, 2012.

Article in En | MEDLINE | ID: mdl-22870271

Subject(s)

CD4-Positive T-Lymphocytes/immunology; CD47 Antigen/immunology; Clonal Deletion; Immunologic Memory; Animals; Antigens, Differentiation/genetics; Antigens, Differentiation/immunology; CD4-Positive T-Lymphocytes/pathology; CD47 Antigen/genetics; Cell Death/genetics; Crohn Disease/genetics; Crohn Disease/immunology; Crohn Disease/pathology; Female; Humans; Interleukin-2/genetics; Interleukin-2/immunology; Male; Mice; Mice, Knockout; Receptors, Immunologic/genetics; Receptors, Immunologic/immunology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD4-Positive T-Lymphocytes / Clonal Deletion / CD47 Antigen / Immunologic Memory Type of study: Prognostic_studies Limits: Animals / Female / Humans / Male Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Canada

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