Alveolar macrophages and Toll-like receptor 4 mediate ventilated lung ischemia reperfusion injury in mice.

Prakash, Arun; Mesa, Kailin R; Wilhelmsen, Kevin; Xu, Fengyun; Dodd-o, Jeffrey M; Hellman, Judith

Prakash, Arun; Mesa, Kailin R; Wilhelmsen, Kevin; Xu, Fengyun; Dodd-o, Jeffrey M; Hellman, Judith.

Affiliation

Prakash A; Department of Anesthesia and Perioperative Care, San Francisco General Hospital, University of California, San Francisco, CA, USA. prakasha@anesthesia.ucsf.edu

Anesthesiology ; 117(4): 822-35, 2012 Oct.

Article in En | MEDLINE | ID: mdl-22890118

Subject(s)

Acute Lung Injury/pathology; Macrophages, Alveolar/physiology; Reperfusion Injury/pathology; Toll-Like Receptor 4/physiology; Acute Lung Injury/etiology; Analgesics, Non-Narcotic/administration & dosage; Analgesics, Non-Narcotic/pharmacology; Animals; CD11 Antigens/genetics; CD11 Antigens/physiology; Cell Line; Clodronic Acid/administration & dosage; Clodronic Acid/pharmacology; Cytokines/metabolism; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Humans; Liposomes; Lung/pathology; Mice; Mice, Knockout; Neutrophil Infiltration; Nutritional Status; Pulmonary Atelectasis/pathology; Pulmonary Circulation/physiology; Real-Time Polymerase Chain Reaction; Respiration, Artificial; Toll-Like Receptor 2/genetics; Toll-Like Receptor 2/physiology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Reperfusion Injury / Macrophages, Alveolar / Toll-Like Receptor 4 / Acute Lung Injury Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Anesthesiology Year: 2012 Document type: Article Affiliation country: United States

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