In silico directed mutagenesis identifies the CD81/claudin-1 hepatitis C virus receptor interface.

Davis, Christopher; Harris, Helen J; Hu, Ke; Drummer, Heidi E; McKeating, Jane A; Mullins, Jonathan G L; Balfe, Peter

Davis, Christopher; Harris, Helen J; Hu, Ke; Drummer, Heidi E; McKeating, Jane A; Mullins, Jonathan G L; Balfe, Peter.

Affiliation

Davis C; School of Immunity and Infection, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK.

Cell Microbiol ; 14(12): 1892-903, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22897233

Subject(s)

Claudin-1/physiology; Hepacivirus/physiology; Mutagenesis, Site-Directed; Receptors, Virus/physiology; Tetraspanin 28/physiology; Virus Internalization; Animals; Cell Line; Claudin-1/genetics; Computational Biology; Computer Simulation; Fluorescence Resonance Energy Transfer; Hepacivirus/pathogenicity; Humans; Models, Molecular; Receptors, Virus/genetics; Tetraspanin 28/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Virus / Mutagenesis, Site-Directed / Hepacivirus / Virus Internalization / Tetraspanin 28 / Claudin-1 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Microbiol Journal subject: MICROBIOLOGIA Year: 2012 Document type: Article Affiliation country: United kingdom

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