Long-lasting oxidative pulmonary insult in rat after intratracheal instillation of silica nanoparticles doped with cadmium.

Coccini, Teresa; Roda, Elisa; Barni, Sergio; Signorini, Cinzia; Manzo, Luigi

Coccini, Teresa; Roda, Elisa; Barni, Sergio; Signorini, Cinzia; Manzo, Luigi.

Affiliation

Coccini T; Salvatore Maugeri Foundation IRCCS Institute of Pavia, and University of Pavia, Toxicology Division and European Centre for Nanomedicine, Pavia, Italy. teresa.coccini@fsm.it

Toxicology ; 302(2-3): 203-11, 2012 Dec 16.

Article in En | MEDLINE | ID: mdl-22898625

Subject(s)

Cadmium/toxicity; Lung/drug effects; Nanoparticles/toxicity; Silicon Dioxide/toxicity; Animals; Bronchoalveolar Lavage Fluid/cytology; Cyclooxygenase 2/genetics; Cyclooxygenase 2/metabolism; F2-Isoprostanes/metabolism; Immunohistochemistry; Lung/metabolism; Male; Microscopy, Electron, Scanning Transmission; Nanoparticles/chemistry; Nitric Oxide Synthase Type II/genetics; Nitric Oxide Synthase Type II/metabolism; Oxidative Stress/drug effects; Rats; Rats, Sprague-Dawley; Silicon Dioxide/chemistry; Superoxide Dismutase/genetics; Superoxide Dismutase/metabolism; Superoxide Dismutase-1; X-Ray Diffraction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cadmium / Silicon Dioxide / Nanoparticles / Lung Limits: Animals Language: En Journal: Toxicology Year: 2012 Document type: Article Affiliation country: Italy Country of publication: Ireland

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