Doxycycline ameliorates the dystrophic phenotype of skeletal and cardiac muscles in mdx mice.

Pereira, Juliano Alves; Taniguti, Ana Paula Tiemi; Matsumura, Cíntia; Marques, Maria Julia; Neto, Humberto Santo

Pereira, Juliano Alves; Taniguti, Ana Paula Tiemi; Matsumura, Cíntia; Marques, Maria Julia; Neto, Humberto Santo.

Affiliation

Pereira JA; Departamento de Anatomia, Biologia Celular, Fisiologia e Biofísica, Instituto de Biologia, Universidade Estadual de Campinas, Campinas, São Paulo, 13083-970, Brazil.

Muscle Nerve ; 46(3): 400-6, 2012 Sep.

Article in En | MEDLINE | ID: mdl-22907231

Subject(s)

Anti-Bacterial Agents/therapeutic use; Doxycycline/therapeutic use; Heart/drug effects; Muscle Strength/drug effects; Muscle, Skeletal/drug effects; Muscular Dystrophy, Animal/drug therapy; Myocardium/pathology; Animals; Anti-Bacterial Agents/pharmacology; Doxycycline/pharmacology; Fibrosis; Heart/physiopathology; Mice; Mice, Inbred mdx; Muscle Strength/physiology; Muscle, Skeletal/pathology; Muscle, Skeletal/physiopathology; Muscular Dystrophy, Animal/pathology; Muscular Dystrophy, Animal/physiopathology; Phenotype

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Doxycycline / Muscle, Skeletal / Muscle Strength / Heart / Anti-Bacterial Agents / Muscular Dystrophy, Animal / Myocardium Limits: Animals Language: En Journal: Muscle Nerve Year: 2012 Document type: Article Affiliation country: Brazil

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