Quantitation and characterization of process impurities and extractables in protein-containing solutions using proton NMR as a general tool.

Skidmore, Ken; Hewitt, Daniel; Kao, Yung-Hsiang

Skidmore, Ken; Hewitt, Daniel; Kao, Yung-Hsiang.

Affiliation

Skidmore K; Department of Protein Analytical Chemistry, Genentech, Inc., South San Francisco, CA 94080, USA. skidmore.ken@gene.com

Biotechnol Prog ; 28(6): 1526-33, 2012.

Article in En | MEDLINE | ID: mdl-22915490

Subject(s)

Drug Contamination/prevention & control; Nuclear Magnetic Resonance, Biomolecular/methods; Proteins/chemistry; Technology, Pharmaceutical/methods; Antibodies, Monoclonal/analysis; Antibodies, Monoclonal/chemistry; Linear Models; Proteins/analysis; Reproducibility of Results

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proteins / Drug Contamination / Technology, Pharmaceutical / Nuclear Magnetic Resonance, Biomolecular Type of study: Prognostic_studies Language: En Journal: Biotechnol Prog Journal subject: BIOTECNOLOGIA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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