Monoclonal antibody therapeutics: history and future.
Curr Opin Pharmacol
; 12(5): 615-22, 2012 Oct.
Article
in En
| MEDLINE
| ID: mdl-22920732
Over the last three decades, monoclonal antibodies have made a dramatic transformation from scientific tools to powerful human therapeutics. At present, approximately 30 therapeutic monoclonal antibodies are marketed in the United States and Europe in a variety of indications, with sales in the US alone reaching approximately $18.5 billion in 2010. This review describes how antibody engineering has revolutionized drug discovery and what are considered the key areas for future development in the monoclonal antibody therapy field.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Antibodies, Monoclonal
Limits:
Animals
/
Humans
Language:
En
Journal:
Curr Opin Pharmacol
Journal subject:
FARMACOLOGIA
Year:
2012
Document type:
Article
Country of publication:
United kingdom