ABC drug transporter and nuclear receptor expression in human cytotrophoblasts: influence of spontaneous syncytialization and induction by glucocorticoids.

Manceau, S; Giraud, C; Declèves, X; Scherrmann, J M; Artiguebieille, F; Goffinet, F; Chappuy, H; Vinot, C; Tréluyer, J M

Manceau, S; Giraud, C; Declèves, X; Scherrmann, J M; Artiguebieille, F; Goffinet, F; Chappuy, H; Vinot, C; Tréluyer, J M.

Affiliation

Manceau S; EA 3620, Université Paris Descartes, Paris, France.

Placenta ; 33(11): 927-32, 2012 Nov.

Article in En | MEDLINE | ID: mdl-22922069

Subject(s)

ATP Binding Cassette Transporter, Subfamily B, Member 1/metabolism; Giant Cells/metabolism; Glucocorticoids/pharmacology; Multidrug Resistance-Associated Proteins/metabolism; Receptors, Glucocorticoid/metabolism; Trophoblasts/metabolism; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1/genetics; Adult; Betamethasone/pharmacology; Cell Nucleus/drug effects; Cell Nucleus/metabolism; Dexamethasone/pharmacology; Down-Regulation/drug effects; Female; Giant Cells/cytology; Humans; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins/genetics; Osmolar Concentration; Placenta/cytology; Placenta/drug effects; Placenta/metabolism; Prednisone/pharmacology; Pregnancy; RNA, Messenger/metabolism; Receptors, Glucocorticoid/genetics; Trophoblasts/cytology; Up-Regulation/drug effects

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Trophoblasts / Receptors, Glucocorticoid / Giant Cells / ATP Binding Cassette Transporter, Subfamily B, Member 1 / Multidrug Resistance-Associated Proteins / Glucocorticoids Limits: Adult / Female / Humans / Pregnancy Language: En Journal: Placenta Year: 2012 Document type: Article Affiliation country: France Country of publication: Netherlands

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