Suppressive effect of calcipotriol on the induction of matrix metalloproteinase (MMP)-9 and MMP-13 in a human squamous cell carcinoma cell line.

Meephansan, J; Komine, M; Tsuda, H; Ohtsuki, M

Meephansan, J; Komine, M; Tsuda, H; Ohtsuki, M.

Affiliation

Meephansan J; Department of Dermatology, Jichi Medical University, Tochigi, Japan.

Clin Exp Dermatol ; 37(8): 889-96, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22924547

Subject(s)

Antineoplastic Agents/pharmacology; Calcitriol/analogs & derivatives; Carcinoma, Squamous Cell/drug therapy; Matrix Metalloproteinase 13/biosynthesis; Matrix Metalloproteinase 9/biosynthesis; Skin Neoplasms/drug therapy; p38 Mitogen-Activated Protein Kinases/metabolism; Calcitriol/pharmacology; Carcinoma, Squamous Cell/enzymology; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Induction/drug effects; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors; Extracellular Signal-Regulated MAP Kinases/metabolism; Humans; Matrix Metalloproteinase 13/genetics; Matrix Metalloproteinase 9/genetics; RNA, Messenger/genetics; RNA, Messenger/metabolism; Signal Transduction/drug effects; Skin Neoplasms/enzymology; Tumor Necrosis Factor-alpha/pharmacology; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Skin Neoplasms / Calcitriol / Carcinoma, Squamous Cell / Matrix Metalloproteinase 9 / P38 Mitogen-Activated Protein Kinases / Matrix Metalloproteinase 13 / Antineoplastic Agents Limits: Humans Language: En Journal: Clin Exp Dermatol Year: 2012 Document type: Article Affiliation country: Japan Country of publication: United kingdom

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