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The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis.
Rubach, Jon K; Cui, Guanglei; Schneck, Jessica L; Taylor, Amy N; Zhao, Baoguang; Smallwood, Angela; Nevins, Neysa; Wisnoski, David; Thrall, Sara H; Meek, Thomas D.
Affiliation
  • Rubach JK; Department of Biological Reagents and Assay Development, GlaxoSmithKline Pharmaceuticals, 1250 South Collegeville Road, Collegeville, PA 19426, USA.
Biochemistry ; 51(38): 7551-68, 2012 Sep 25.
Article in En | MEDLINE | ID: mdl-22928782
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cathepsin C / Dipeptides / Amino Acids Limits: Humans Language: En Journal: Biochemistry Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cathepsin C / Dipeptides / Amino Acids Limits: Humans Language: En Journal: Biochemistry Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States