Exosome-mediated shuttling of microRNA-29 regulates HIV Tat and morphine-mediated neuronal dysfunction.

Hu, G; Yao, H; Chaudhuri, A D; Duan, M; Yelamanchili, S V; Wen, H; Cheney, P D; Fox, H S; Buch, S

Hu, G; Yao, H; Chaudhuri, A D; Duan, M; Yelamanchili, S V; Wen, H; Cheney, P D; Fox, H S; Buch, S.

Affiliation

Hu G; Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5880, USA.

Cell Death Dis ; 3: e381, 2012 Aug 30.

Article in En | MEDLINE | ID: mdl-22932723

Subject(s)

Analgesics, Opioid/pharmacology; Exosomes/metabolism; Gene Expression Regulation; MicroRNAs/metabolism; Morphine/pharmacology; Neurons/metabolism; tat Gene Products, Human Immunodeficiency Virus/metabolism; 3' Untranslated Regions; Animals; Astrocytes/metabolism; Cells, Cultured; Disease Models, Animal; Down-Regulation/drug effects; Ganglia/drug effects; Ganglia/metabolism; Humans; Macaca mulatta; Neurons/drug effects; Proto-Oncogene Proteins c-sis/genetics; Proto-Oncogene Proteins c-sis/metabolism; Rats; Simian Immunodeficiency Virus/pathogenicity; Transfection; tat Gene Products, Human Immunodeficiency Virus/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation / MicroRNAs / Tat Gene Products, Human Immunodeficiency Virus / Exosomes / Analgesics, Opioid / Morphine / Neurons Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Cell Death Dis Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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