Altered MAPK signaling in progressive deterioration of endothelial function in diabetic mice.

Huang, An; Yang, Yang-Ming; Yan, Changdong; Kaley, Gabor; Hintze, Thomas H; Sun, Dong

Huang, An; Yang, Yang-Ming; Yan, Changdong; Kaley, Gabor; Hintze, Thomas H; Sun, Dong.

Affiliation

Huang A; Department of Physiology, New York Medical College, Valhalla, New York, USA. an_huang@nymc.edu

Diabetes ; 61(12): 3181-8, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22933112

Subject(s)

Diabetes Mellitus, Type 2/metabolism; Mitogen-Activated Protein Kinases/metabolism; Animals; Anthracenes/therapeutic use; Butadienes/therapeutic use; Diabetes Mellitus, Type 2/drug therapy; Extracellular Signal-Regulated MAP Kinases/antagonists & inhibitors; Extracellular Signal-Regulated MAP Kinases/metabolism; Imidazoles/therapeutic use; Immunoblotting; JNK Mitogen-Activated Protein Kinases/antagonists & inhibitors; JNK Mitogen-Activated Protein Kinases/metabolism; Male; Mice; Nitriles/therapeutic use; Oxidative Stress/drug effects; Phosphorylation/drug effects; Phosphorylation/genetics; Pyridines/therapeutic use; Receptors, Leptin/genetics; Receptors, Leptin/metabolism; Resveratrol; Signal Transduction/drug effects; Stilbenes/therapeutic use; Superoxides/metabolism; p38 Mitogen-Activated Protein Kinases/antagonists & inhibitors; p38 Mitogen-Activated Protein Kinases/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Mitogen-Activated Protein Kinases / Diabetes Mellitus, Type 2 Limits: Animals Language: En Journal: Diabetes Year: 2012 Document type: Article Affiliation country: United States

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