Corticosterone suppresses the proliferation of BV2 microglia cells via glucocorticoid, but not mineralocorticoid receptor.

Nakatani, Yoshihiko; Amano, Taku; Tsuji, Minoru; Takeda, Hiroshi

Nakatani, Yoshihiko; Amano, Taku; Tsuji, Minoru; Takeda, Hiroshi.

Affiliation

Nakatani Y; Department of Pharmacology, School of Pharmacy, International University of Health and Welfare, Kitakanemaru, Ohtawara, Tochigi, Japan. ynakatani@iuhw.ac.jp

Life Sci ; 91(15-16): 761-70, 2012 Oct 22.

Article in En | MEDLINE | ID: mdl-22940619

Subject(s)

Corticosterone/metabolism; Microglia/cytology; Microglia/metabolism; Receptors, Glucocorticoid/immunology; Receptors, Mineralocorticoid/metabolism; Animals; Anti-Inflammatory Agents/adverse effects; Cell Line; Cell Proliferation/drug effects; L-Lactate Dehydrogenase/immunology; Membrane Potential, Mitochondrial; Mice; Microglia/drug effects; Mifepristone/pharmacology; Mineralocorticoid Receptor Antagonists/pharmacology; Receptors, Glucocorticoid/antagonists & inhibitors; Spironolactone/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Corticosterone / Receptors, Glucocorticoid / Receptors, Mineralocorticoid / Microglia Limits: Animals Language: En Journal: Life Sci Year: 2012 Document type: Article Affiliation country: Japan Country of publication: Netherlands

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