Suboptimal maternal nutrition during early fetal kidney development specifically promotes renal lipid accumulation following juvenile obesity in the offspring.

Fainberg, H P; Sharkey, D; Sebert, S; Wilson, V; Pope, M; Budge, H; Symonds, M E

Fainberg, H P; Sharkey, D; Sebert, S; Wilson, V; Pope, M; Budge, H; Symonds, M E.

Affiliation

Fainberg HP; Early Life Nutrition Research Unit, Academic Child Health, School of Medicine, University Hospital, Nottingham NG7 2UH, UK.

Reprod Fertil Dev ; 25(5): 728-36, 2013.

Article in En | MEDLINE | ID: mdl-22951182

Subject(s)

Fetal Development/physiology; Insulin Resistance/physiology; Kidney/embryology; Lipids/analysis; Maternal Nutritional Physiological Phenomena/physiology; Obesity/physiopathology; Animals; Blotting, Western; DNA Primers/genetics; Female; Hypoxia-Inducible Factor 1, alpha Subunit/metabolism; Immunohistochemistry; Kidney/chemistry; Pregnancy; Real-Time Polymerase Chain Reaction; Sheep; Statistics, Nonparametric; Triglycerides/analysis; Voltage-Dependent Anion Channel 1/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Insulin Resistance / Maternal Nutritional Physiological Phenomena / Fetal Development / Kidney / Lipids / Obesity Limits: Animals / Pregnancy Language: En Journal: Reprod Fertil Dev Journal subject: MEDICINA REPRODUTIVA Year: 2013 Document type: Article Affiliation country: United kingdom

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