Central mechanisms of menthol-induced analgesia.

Pan, Rong; Tian, Yuzhen; Gao, Ruby; Li, Haitao; Zhao, Xianguo; Barrett, James E; Hu, Huijuan

Pan, Rong; Tian, Yuzhen; Gao, Ruby; Li, Haitao; Zhao, Xianguo; Barrett, James E; Hu, Huijuan.

Affiliation

Pan R; Department of Pharmacology and Physiology, Drexel University College of Medicine, Philadelphia, PA 19102, USA.

J Pharmacol Exp Ther ; 343(3): 661-72, 2012 Dec.

Article in En | MEDLINE | ID: mdl-22951274

Subject(s)

Analgesia/methods; Calcium Channel Blockers/therapeutic use; Menthol/therapeutic use; Neuralgia/drug therapy; Pain Threshold/drug effects; Voltage-Gated Sodium Channel Blockers/therapeutic use; Action Potentials/drug effects; Animals; Behavior, Animal/drug effects; Brain/drug effects; Brain/metabolism; Calcium Channel Blockers/pharmacokinetics; Calcium Channel Blockers/pharmacology; Calcium Channels/metabolism; Cells, Cultured; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; GABA-A Receptor Agonists/pharmacology; GABA-A Receptor Agonists/therapeutic use; Male; Mass Spectrometry; Menthol/pharmacokinetics; Menthol/pharmacology; Mice; Mice, Inbred Strains; Neuralgia/metabolism; Neuralgia/psychology; Pain Measurement; Pain Threshold/psychology; Posterior Horn Cells/drug effects; Posterior Horn Cells/metabolism; Receptors, GABA-A/metabolism; Voltage-Gated Sodium Channel Blockers/pharmacokinetics; Voltage-Gated Sodium Channel Blockers/pharmacology; Voltage-Gated Sodium Channels/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Calcium Channel Blockers / Pain Threshold / Voltage-Gated Sodium Channel Blockers / Analgesia / Menthol / Neuralgia Limits: Animals Language: En Journal: J Pharmacol Exp Ther Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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