Deletion of the huntingtin proline-rich region does not significantly affect normal huntingtin function in mice.

Neveklovska, Michelle; Clabough, Erin B D; Steffan, Joan S; Zeitlin, Scott O

Neveklovska, Michelle; Clabough, Erin B D; Steffan, Joan S; Zeitlin, Scott O.

Affiliation

Neveklovska M; Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, Virginia, USA.

J Huntingtons Dis ; 1(1): 71-87, 2012.

Article in En | MEDLINE | ID: mdl-22956985

Subject(s)

Nerve Tissue Proteins/genetics; Nerve Tissue Proteins/physiology; Nuclear Proteins/genetics; Nuclear Proteins/physiology; Proline-Rich Protein Domains/genetics; Proline/genetics; Sequence Deletion/genetics; Amino Acid Sequence; Animals; Base Sequence; Behavior, Animal; Disease Models, Animal; Huntingtin Protein; Huntington Disease; Intracellular Space/metabolism; Mice; Mice, Transgenic; Molecular Sequence Data; Nerve Tissue Proteins/chemistry; Nerve Tissue Proteins/metabolism; Nuclear Proteins/chemistry; Nuclear Proteins/metabolism; Phosphorylation; Proline/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Proline / Nuclear Proteins / Sequence Deletion / Proline-Rich Protein Domains / Nerve Tissue Proteins Limits: Animals Language: En Journal: J Huntingtons Dis Year: 2012 Document type: Article Affiliation country: United States Country of publication: Netherlands

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