Multiple facets of the DNA damage response contribute to the radioresistance of mouse mesenchymal stromal cell lines.

Sugrue, Tara; Brown, James A L; Lowndes, Noel F; Ceredig, Rhodri

Sugrue, Tara; Brown, James A L; Lowndes, Noel F; Ceredig, Rhodri.

Affiliation

Sugrue T; Physiology Department, Regenerative Medicine Institute, National Centre of Biomedical Engineering Science and School of Medicine, Nursing and Health Sciences, National University of Ireland, Galway, Galway, Ireland.

Stem Cells ; 31(1): 137-45, 2013 Jan.

Article in En | MEDLINE | ID: mdl-22961695

Subject(s)

DNA Damage/radiation effects; DNA Repair/radiation effects; Mesenchymal Stem Cells/radiation effects; Radiation Tolerance/physiology; Animals; Ataxia Telangiectasia Mutated Proteins; CD4-Positive T-Lymphocytes/radiation effects; CD8-Positive T-Lymphocytes/radiation effects; Cell Cycle Checkpoints; Cell Cycle Proteins/biosynthesis; Cell Differentiation/radiation effects; Cell Line; Cell Proliferation/radiation effects; Checkpoint Kinase 2; DNA Breaks, Double-Stranded/radiation effects; DNA Ligase ATP; DNA Ligases/biosynthesis; DNA-Binding Proteins/biosynthesis; Histones/biosynthesis; Histones/metabolism; Mesenchymal Stem Cells/cytology; Mice; Protein Serine-Threonine Kinases/biosynthesis; Proto-Oncogene Proteins c-bcl-2/biosynthesis; Radiation, Ionizing; Signal Transduction; Tumor Suppressor Proteins/biosynthesis; bcl-X Protein/biosynthesis

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Radiation Tolerance / DNA Damage / DNA Repair / Mesenchymal Stem Cells Limits: Animals Language: En Journal: Stem Cells Year: 2013 Document type: Article Affiliation country: Ireland Country of publication: United kingdom

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google