[Alveolar hemorrhage]. / Hémorragie intra-alvéolaire.
Rev Med Interne
; 34(4): 214-23, 2013 Apr.
Article
in Fr
| MEDLINE
| ID: mdl-22963805
ABSTRACT
Diffuse alveolar hemorrhage (DAH) is defined by the presence of red blood cells originating from the lung capillaries or venules within the alveoli. The diagnosis is established on clinical features, radiological pattern, and especially bronchoalveolar lavage. Diffuse alveolar hemorrhage may have many immune or non-immune causes. Immune causes of DAH include vasculitides, connective tissue diseases, especially systemic lupus erythematosus, and antiglomerular basement membrane antibody disease (Goodpasture's syndrome). Treatment is both supportive and causal, often based on high dose corticosteroids and immunosuppressive therapy (especially intravenous cyclophosphamide). Plasma exchanges are performed in antiglomerular basement membrane antibody disease and systemic lupus erythematosus, and are considered in systemic vasculitis. Non-immune causes of DAH mainly include heart diseases, coagulation disorders, infections, drug toxicities and idiopathic DAH. Treatment of non-immune DAH is that of its cause. Whatever the cause, DAH is an emergency requiring prompt assessment and early treatment.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pulmonary Alveoli
/
Hemorrhage
/
Lung Diseases
Type of study:
Diagnostic_studies
Limits:
Humans
Language:
Fr
Journal:
Rev Med Interne
Year:
2013
Document type:
Article
Affiliation country:
France