Synthesis and antiviral activity of 3'-heterocyclic substituted 3'-deoxythymidines.

Wigerinck, P; Van Aerschot, A; Janssen, G; Claes, P; Balzarini, J; De Clercq, E; Herdewijn, P

Wigerinck, P; Van Aerschot, A; Janssen, G; Claes, P; Balzarini, J; De Clercq, E; Herdewijn, P.

Affiliation

Wigerinck P; Rega Institute for Medical Research, Katholieke Universiteit Leuven, Belgium.

J Med Chem ; 33(2): 868-73, 1990 Feb.

Article in En | MEDLINE | ID: mdl-2299650

Subject(s)

Antiviral Agents/chemical synthesis; Thymidine/analogs & derivatives; Animals; Cell Transformation, Viral/drug effects; Cells, Cultured; Chemical Phenomena; Chemistry; Cytopathogenic Effect, Viral/drug effects; HIV/drug effects; Humans; In Vitro Techniques; Mice; Structure-Activity Relationship; Virus Replication/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Antiviral Agents / Thymidine Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 1990 Document type: Article Affiliation country: Belgium Country of publication: United States

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