Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis, and biological evaluation.

Patra, Malay; Ingram, Katrin; Pierroz, Vanessa; Ferrari, Stefano; Spingler, Bernhard; Keiser, Jennifer; Gasser, Gilles

Patra, Malay; Ingram, Katrin; Pierroz, Vanessa; Ferrari, Stefano; Spingler, Bernhard; Keiser, Jennifer; Gasser, Gilles.

Affiliation

Patra M; Institute of Inorganic Chemistry, University of Zurich , Winterthurerstrasse 190, CH-8057 Zurich, Switzerland.

J Med Chem ; 55(20): 8790-8, 2012 Oct 25.

Article in En | MEDLINE | ID: mdl-23005702

Subject(s)

Ferrous Compounds/chemical synthesis; Praziquantel/analogs & derivatives; Praziquantel/chemical synthesis; Schistosomicides/chemical synthesis; Animals; Cell Line, Tumor; Crystallography, X-Ray; Ferrous Compounds/pharmacology; Humans; Metallocenes; Models, Molecular; Molecular Structure; Praziquantel/pharmacology; Schistosoma mansoni/drug effects; Schistosomicides/pharmacology; Stereoisomerism; Structure-Activity Relationship

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Praziquantel / Schistosomicides / Ferrous Compounds Limits: Animals / Humans Language: En Journal: J Med Chem Journal subject: QUIMICA Year: 2012 Document type: Article Affiliation country: Switzerland Country of publication: United States

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