The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression and function in the proximal tubule.

Jenkinson, Sarah E; Chung, Git W; van Loon, Ellen; Bakar, Nur S; Dalzell, Abigail M; Brown, Colin D A

Jenkinson, Sarah E; Chung, Git W; van Loon, Ellen; Bakar, Nur S; Dalzell, Abigail M; Brown, Colin D A.

Affiliation

Jenkinson SE; Epithelial Cell Research Group, Institute for Cell and Molecular Biosciences, Medical School, Framlington Place, Newcastle upon Tyne, UK. sarah.jenkinson@newcastle.ac.uk

Pflugers Arch ; 464(6): 601-11, 2012 Dec.

Article in En | MEDLINE | ID: mdl-23014881

Subject(s)

Epithelial Cells/metabolism; Kidney Tubules, Proximal/metabolism; Membrane Transport Proteins/biosynthesis; ATP Binding Cassette Transporter, Subfamily B/biosynthesis; ATP Binding Cassette Transporter, Subfamily B/genetics; ATP Binding Cassette Transporter, Subfamily B/metabolism; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters/biosynthesis; ATP-Binding Cassette Transporters/genetics; ATP-Binding Cassette Transporters/metabolism; Biological Transport; Cell Line; Humans; Kidney Cortex/cytology; Kidney Cortex/metabolism; Kidney Tubules, Proximal/cytology; Membrane Transport Proteins/genetics; Membrane Transport Proteins/metabolism; Monocarboxylic Acid Transporters/biosynthesis; Monocarboxylic Acid Transporters/genetics; Monocarboxylic Acid Transporters/metabolism; Neoplasm Proteins/biosynthesis; Neoplasm Proteins/genetics; Neoplasm Proteins/metabolism; RNA, Messenger/genetics; Symporters/biosynthesis; Symporters/genetics; Symporters/metabolism

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Transport Proteins / Epithelial Cells / Kidney Tubules, Proximal Limits: Humans Language: En Journal: Pflugers Arch Year: 2012 Document type: Article Affiliation country: United kingdom Country of publication: Germany

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google