Evolutionary imprint of catalytic domains in fungal PKS-NRPS hybrids.

Boettger, Daniela; Bergmann, Holger; Kuehn, Barbara; Shelest, Ekaterina; Hertweck, Christian

Boettger, Daniela; Bergmann, Holger; Kuehn, Barbara; Shelest, Ekaterina; Hertweck, Christian.

Affiliation

Boettger D; Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology-, Hans Knöll Institute, Beutenbergstrasse 11a, 07743 Jena, Germany.

Chembiochem ; 13(16): 2363-73, 2012 Nov 05.

Article in En | MEDLINE | ID: mdl-23023987

Subject(s)

Aspergillus/enzymology; Biological Evolution; Peptide Synthases/metabolism; Polyketide Synthases/metabolism; Amino Acids/chemistry; Aspergillus/genetics; Aspergillus/metabolism; Biocatalysis; Computational Biology; Indole Alkaloids/chemistry; Lovastatin/chemistry; Models, Molecular; Molecular Conformation; Peptide Synthases/analysis; Peptide Synthases/genetics; Phylogeny; Polyketide Synthases/analysis; Polyketide Synthases/genetics; Polyketides/chemistry; Sequence Alignment

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Synthases / Aspergillus / Polyketide Synthases / Biological Evolution Type of study: Prognostic_studies Language: En Journal: Chembiochem Journal subject: BIOQUIMICA Year: 2012 Document type: Article Affiliation country: Germany

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