Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.

Langer, Marybeth; Duggan, Elizabeth Stewart; Booth, John Leland; Patel, Vineet Indrajit; Zander, Ryan A; Silasi-Mansat, Robert; Ramani, Vijay; Veres, Tibor Zoltan; Prenzler, Frauke; Sewald, Katherina; Williams, Daniel M; Coggeshall, Kenneth Mark; Awasthi, Shanjana; Lupu, Florea; Burian, Dennis; Ballard, Jimmy Dale; Braun, Armin; Metcalf, Jordan Patrick

Langer, Marybeth; Duggan, Elizabeth Stewart; Booth, John Leland; Patel, Vineet Indrajit; Zander, Ryan A; Silasi-Mansat, Robert; Ramani, Vijay; Veres, Tibor Zoltan; Prenzler, Frauke; Sewald, Katherina; Williams, Daniel M; Coggeshall, Kenneth Mark; Awasthi, Shanjana; Lupu, Florea; Burian, Dennis; Ballard, Jimmy Dale; Braun, Armin; Metcalf, Jordan Patrick.

Affiliation

Langer M; Pulmonary and Critical Care Division of the Department of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

Infect Immun ; 80(12): 4374-87, 2012 Dec.

Article in En | MEDLINE | ID: mdl-23027535

Subject(s)

Alveolar Epithelial Cells/drug effects; Anthrax/pathology; Antigens, Bacterial/toxicity; Bacillus anthracis/pathogenicity; Bacterial Toxins/toxicity; Respiratory Tract Infections/pathology; Actins/metabolism; Alveolar Epithelial Cells/cytology; Alveolar Epithelial Cells/metabolism; Alveolar Epithelial Cells/microbiology; Animals; Anthrax/microbiology; Antigens, Bacterial/genetics; Bacillus anthracis/genetics; Bacillus anthracis/metabolism; Bacterial Toxins/genetics; Calcium-Binding Proteins/genetics; Calcium-Binding Proteins/metabolism; Cells, Cultured; Humans; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; Mixed Function Oxygenases/genetics; Mixed Function Oxygenases/metabolism; Muscle Proteins/genetics; Muscle Proteins/metabolism; Receptors, Peptide/genetics; Receptors, Peptide/metabolism; Respiratory Tract Infections/microbiology; Virulence

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Tract Infections / Bacillus anthracis / Bacterial Toxins / Alveolar Epithelial Cells / Anthrax / Antigens, Bacterial Limits: Animals / Humans Language: En Journal: Infect Immun Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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