Local structure and global patterning of Cu2+ binding in fibrillar amyloid-ß [Aß(1-40)] protein.

Gunderson, William A; Hernández-Guzmán, Jessica; Karr, Jesse W; Sun, Li; Szalai, Veronika A; Warncke, Kurt

Gunderson, William A; Hernández-Guzmán, Jessica; Karr, Jesse W; Sun, Li; Szalai, Veronika A; Warncke, Kurt.

Affiliation

Gunderson WA; Department of Physics, Emory University, Atlanta, Georgia 30322, USA.

J Am Chem Soc ; 134(44): 18330-7, 2012 Nov 07.

Article in En | MEDLINE | ID: mdl-23043377

Subject(s)

Amyloid beta-Peptides/chemistry; Amyloid beta-Peptides/metabolism; Copper/metabolism; Peptide Fragments/chemistry; Peptide Fragments/metabolism; Alzheimer Disease/metabolism; Binding Sites; Electron Spin Resonance Spectroscopy; Histidine/chemistry; Histidine/metabolism; Humans; Models, Molecular; Protein Binding; Protein Structure, Secondary; Reactive Oxygen Species/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Peptide Fragments / Amyloid beta-Peptides / Copper Limits: Humans Language: En Journal: J Am Chem Soc Year: 2012 Document type: Article Affiliation country: United States

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