Efficiency of immunotoxin cytotoxicity is modulated by the intracellular itinerary.

Tortorella, Lori L; Pipalia, Nina H; Mukherjee, Sushmita; Pastan, Ira; Fitzgerald, David; Maxfield, Frederick R

Tortorella, Lori L; Pipalia, Nina H; Mukherjee, Sushmita; Pastan, Ira; Fitzgerald, David; Maxfield, Frederick R.

Affiliation

Tortorella LL; Department of Biochemistry, Weill Cornell Medical College, New York, New York, United States of America.

PLoS One ; 7(10): e47320, 2012.

Article in En | MEDLINE | ID: mdl-23056628

Subject(s)

Furin/metabolism; Immunotoxins/metabolism; Membrane Glycoproteins/metabolism; Animals; Antibodies, Monoclonal/metabolism; CHO Cells; Cell Survival/genetics; Cell Survival/physiology; Cricetinae; Exotoxins/metabolism; Fluorescent Antibody Technique, Indirect; Furin/genetics; Humans; Immunoblotting; Immunotoxins/genetics; Membrane Glycoproteins/genetics; Receptors, Transferrin/genetics; Receptors, Transferrin/metabolism

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Membrane Glycoproteins / Immunotoxins / Furin Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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