A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A)  receptors.

Jensen, M L; Wafford, K A; Brown, A R; Belelli, D; Lambert, J J; Mirza, N R

A study of subunit selectivity, mechanism and site of action of the delta selective compound 2 (DS2) at human recombinant and rodent native GABA(A) receptors.

Jensen, M L; Wafford, K A; Brown, A R; Belelli, D; Lambert, J J; Mirza, N R.

Affiliation

Jensen ML; NeuroSearch A/S, Ballerup, Denmark.

Br J Pharmacol ; 168(5): 1118-32, 2013 Mar.

Article in En | MEDLINE | ID: mdl-23061935

Subject(s)

Protein Subunits/physiology; Pyridines/pharmacology; Receptors, GABA-A/physiology; Allosteric Regulation; Animals; Brain/drug effects; Brain/physiology; Female; HEK293 Cells; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oocytes/drug effects; Oocytes/physiology; Rats; Recombinant Proteins; Xenopus laevis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyridines / Receptors, GABA-A / Protein Subunits Limits: Animals / Female / Humans / Male Language: En Journal: Br J Pharmacol Year: 2013 Document type: Article Affiliation country: Denmark Country of publication: United kingdom

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