Characterization of arylalkylamine N-acetyltransferase from silkmoth (Antheraea pernyi) and pesticidal drug design based on the baculovirus-expressed enzyme.

Tsugehara, Taketo; Imai, Tetsuya; Takeda, Makio

Tsugehara, Taketo; Imai, Tetsuya; Takeda, Makio.

Affiliation

Tsugehara T; Graduate School of Natural Science and Technology, Kobe University, Rokkodai-cho, Nadaku, Japan.

Comp Biochem Physiol C Toxicol Pharmacol ; 157(1): 93-102, 2013 Jan.

Article in En | MEDLINE | ID: mdl-23064182

Subject(s)

Arylalkylamine N-Acetyltransferase/metabolism; Drug Design; Insect Proteins/metabolism; Moths/enzymology; Acetylation; Amino Acid Sequence; Animals; Arylalkylamine N-Acetyltransferase/classification; Arylalkylamine N-Acetyltransferase/genetics; Baculoviridae/genetics; Base Sequence; Biocatalysis/drug effects; Biogenic Monoamines/metabolism; Blotting, Western; DNA, Complementary/genetics; Enzyme Inhibitors/metabolism; Enzyme Inhibitors/pharmacology; Genetic Vectors/genetics; Insect Proteins/antagonists & inhibitors; Insect Proteins/genetics; Kinetics; Molecular Sequence Data; Moths/genetics; Pesticides/chemistry; Pesticides/pharmacology; Phylogeny; Sequence Homology, Amino Acid; Sf9 Cells; Substrate Specificity; Tryptamines/metabolism; Tryptamines/pharmacology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Drug Design / Insect Proteins / Arylalkylamine N-Acetyltransferase / Moths Limits: Animals Language: En Journal: Comp Biochem Physiol C Toxicol Pharmacol Journal subject: FARMACOLOGIA / TOXICOLOGIA Year: 2013 Document type: Article Affiliation country: Japan

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