Do acetyl salicylic acid and terbutaline in combination increase the probability of a clinical pregnancy in patients undergoing IVF/ICSI?
J Obstet Gynaecol
; 32(8): 786-9, 2012 Nov.
Article
in En
| MEDLINE
| ID: mdl-23075357
ABSTRACT
The present study investigated if acetyl salicylic acid (ASA) and terbutaline in combination increased the clinical pregnancy rate in patients undergoing in vitro fertilisation (IVF)/intra-cytoplasmic sperm injection (ICSI). A randomised controlled trial was designed, in which 167 patients were randomised to taking ASA for 9 weeks after embryo transfer and terbutaline around the time of embryo transfer as adjuvant medication. A total of 112 patients were randomised to no adjuvant medication. The clinical pregnancy rate per controlled ovarian hyperstimulation was 30.5% in the intervention group and 42.0% in the control group. This difference was not statistically significant, and we conclude that ASA and terbutaline in combination do not increase the clinical pregnancy rate after IVF/ICSI treatment.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Terbutaline
/
Anti-Inflammatory Agents, Non-Steroidal
/
Aspirin
/
Sperm Injections, Intracytoplasmic
/
Adrenergic beta-2 Receptor Agonists
Type of study:
Clinical_trials
Limits:
Adult
/
Female
/
Humans
/
Pregnancy
Language:
En
Journal:
J Obstet Gynaecol
Year:
2012
Document type:
Article
Affiliation country:
Norway