The pharmacokinetics and pharmacodynamics of liposome bupivacaine administered via a single epidural injection to healthy volunteers.

Viscusi, Eugene R; Candiotti, Keith A; Onel, Erol; Morren, Michael; Ludbrook, Guy L

Viscusi, Eugene R; Candiotti, Keith A; Onel, Erol; Morren, Michael; Ludbrook, Guy L.

Affiliation

Viscusi ER; Acute Pain Management, Department of Anesthesiology, Thomas Jefferson University, Philadelphia, PA 19107, USA. eugene.viscusi@jefferson.edu

Reg Anesth Pain Med ; 37(6): 616-22, 2012.

Article in En | MEDLINE | ID: mdl-23080351

Subject(s)

Anesthetics, Local/administration & dosage; Anesthetics, Local/pharmacokinetics; Bupivacaine/administration & dosage; Bupivacaine/pharmacokinetics; Injections, Epidural; Adult; Anesthetics, Local/blood; Area Under Curve; Bupivacaine/blood; Cold Temperature; Dose-Response Relationship, Drug; Double-Blind Method; Half-Life; Humans; Liposomes; Nerve Block; Time Factors; Touch; Walking

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Injections, Epidural / Bupivacaine / Anesthetics, Local Type of study: Clinical_trials / Prognostic_studies Limits: Adult / Humans Language: En Journal: Reg Anesth Pain Med Journal subject: ANESTESIOLOGIA / NEUROLOGIA / PSICOFISIOLOGIA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United kingdom

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