The effect of alpha-v integrin inhibition on the malignant characteristics of medulloblastoma.

Thompson, Eric M; Whitney, Nathaniel L; Wu, Y Jeffrey; Neuwelt, Edward A

Thompson, Eric M; Whitney, Nathaniel L; Wu, Y Jeffrey; Neuwelt, Edward A.

Affiliation

Thompson EM; Department of Neurological Surgery, Oregon Health & Science University, Portland, OR, USA.

J Neurosurg Pediatr ; 11(1): 60-7, 2013 Jan.

Article in En | MEDLINE | ID: mdl-23082872

Subject(s)

Cerebellar Neoplasms/drug therapy; Cerebellar Neoplasms/pathology; Integrin alpha5/drug effects; Medulloblastoma/drug therapy; Medulloblastoma/pathology; Antibodies, Monoclonal/therapeutic use; Antibodies, Monoclonal, Humanized; Blotting, Western; Cell Adhesion/drug effects; Cell Line; Cell Movement/drug effects; Cell Proliferation/drug effects; Dose-Response Relationship, Drug; Enzyme-Linked Immunosorbent Assay; Humans; Hypoxia/pathology; Hypoxia-Inducible Factor 1, alpha Subunit/physiology; Phenotype; Proto-Oncogene Proteins c-myc/biosynthesis; Proto-Oncogene Proteins c-myc/genetics; Vascular Endothelial Growth Factor A/biosynthesis; Vascular Endothelial Growth Factor A/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cerebellar Neoplasms / Integrin alpha5 / Medulloblastoma Limits: Humans Language: En Journal: J Neurosurg Pediatr Journal subject: NEUROCIRURGIA / PEDIATRIA Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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