Persistent dystrophin protein restoration 90 days after a course of intraperitoneally administered naked 2'OMePS AON and ZM2 NP-AON complexes in mdx mice.

Bassi, Elena; Falzarano, Sofia; Fabris, Marina; Gualandi, Francesca; Merlini, Luciano; Vattemi, Gaetano; Perrone, Daniela; Marchesi, Elena; Sabatelli, Patrizia; Sparnacci, Katia; Laus, Michele; Bonaldo, Paolo; Rimessi, Paola; Braghetta, Paola; Ferlini, Alessandra

Persistent dystrophin protein restoration 90 days after a course of intraperitoneally administered naked 2'OMePS AON and ZM2 NP-AON complexes in mdx mice.

Bassi, Elena; Falzarano, Sofia; Fabris, Marina; Gualandi, Francesca; Merlini, Luciano; Vattemi, Gaetano; Perrone, Daniela; Marchesi, Elena; Sabatelli, Patrizia; Sparnacci, Katia; Laus, Michele; Bonaldo, Paolo; Rimessi, Paola; Braghetta, Paola; Ferlini, Alessandra.

Affiliation

Bassi E; Department of Experimental and Diagnostic Medicine, Section of Medical Genetics, University of Ferrara, Via Fossato di Mortara 74, 44100 Ferrara, Italy.

J Biomed Biotechnol ; 2012: 897076, 2012.

Article in En | MEDLINE | ID: mdl-23091362

Subject(s)

Dystrophin/metabolism; Muscular Dystrophy, Duchenne/drug therapy; Muscular Dystrophy, Duchenne/metabolism; Nanocapsules/administration & dosage; Oligonucleotides, Antisense/administration & dosage; Animals; Dystrophin/genetics; Injections, Intraperitoneal; Mice; Mice, Inbred mdx; Treatment Outcome; Up-Regulation/drug effects; Up-Regulation/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dystrophin / Oligonucleotides, Antisense / Muscular Dystrophy, Duchenne / Nanocapsules Limits: Animals Language: En Journal: J Biomed Biotechnol Journal subject: BIOTECNOLOGIA / MEDICINA Year: 2012 Document type: Article Affiliation country: Italy Country of publication: United States

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