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Mutations in multiple domains of Gag drive the emergence of in vitro resistance to the phosphonate-containing HIV-1 protease inhibitor GS-8374.
Stray, Kirsten M; Callebaut, Christian; Glass, Bärbel; Tsai, Luong; Xu, Lianhong; Müller, Barbara; Kräusslich, Hans-Georg; Cihlar, Tomas.
Affiliation
  • Stray KM; Gilead Sciences, Inc., Foster City, California, USA. kirsten.stray@gilead.com
J Virol ; 87(1): 454-63, 2013 Jan.
Article in En | MEDLINE | ID: mdl-23097440
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV-1 / HIV Protease Inhibitors / Anti-HIV Agents / Mutation, Missense / Drug Resistance, Viral / Gag Gene Products, Human Immunodeficiency Virus Limits: Humans Language: En Journal: J Virol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: HIV-1 / HIV Protease Inhibitors / Anti-HIV Agents / Mutation, Missense / Drug Resistance, Viral / Gag Gene Products, Human Immunodeficiency Virus Limits: Humans Language: En Journal: J Virol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States