Deficiency of the microglial receptor CX3CR1 impairs postnatal functional development of thalamocortical synapses in the barrel cortex.

Hoshiko, Maki; Arnoux, Isabelle; Avignone, Elena; Yamamoto, Nobuhiko; Audinat, Etienne

Hoshiko, Maki; Arnoux, Isabelle; Avignone, Elena; Yamamoto, Nobuhiko; Audinat, Etienne.

Affiliation

Hoshiko M; Institut National de la Santé et de la Recherche Médicale, U603, 75006 Paris, France.

J Neurosci ; 32(43): 15106-11, 2012 Oct 24.

Article in En | MEDLINE | ID: mdl-23100431

Subject(s)

Developmental Disabilities/pathology; Receptors, Chemokine/deficiency; Somatosensory Cortex/pathology; Synapses/pathology; Thalamus/pathology; Age Factors; Animals; Animals, Newborn; CX3C Chemokine Receptor 1; Chemokine CX3CL1/metabolism; Developmental Disabilities/genetics; Electric Stimulation; Excitatory Amino Acid Antagonists/pharmacology; Excitatory Postsynaptic Potentials/genetics; Excitatory Postsynaptic Potentials/physiology; Female; GABA Antagonists/pharmacology; Gene Expression Regulation, Developmental/genetics; Green Fluorescent Proteins/genetics; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia/metabolism; Receptors, Chemokine/genetics; Serotonin Plasma Membrane Transport Proteins/metabolism; Statistics, Nonparametric

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Somatosensory Cortex / Synapses / Thalamus / Developmental Disabilities / Receptors, Chemokine Limits: Animals Language: En Journal: J Neurosci Year: 2012 Document type: Article Affiliation country: France

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