An analogue of resveratrol HS-1793 exhibits anticancer activity against MCF-7 cells via inhibition of mitochondrial biogenesis gene expression.

Jeong, Seung Hun; Song, In Sung; Kim, Hyoung Kyu; Lee, Sung Ryul; Song, Suhee; Suh, Hongsuk; Yoon, Young Geol; Yoo, Young Hyun; Kim, Nari; Rhee, Byoung Doo; Ko, Kyung Soo; Han, Jin

Jeong, Seung Hun; Song, In Sung; Kim, Hyoung Kyu; Lee, Sung Ryul; Song, Suhee; Suh, Hongsuk; Yoon, Young Geol; Yoo, Young Hyun; Kim, Nari; Rhee, Byoung Doo; Ko, Kyung Soo; Han, Jin.

Affiliation

Jeong SH; National Research Laboratory for Mitochondrial Signaling, Department of Physiology, College of Medicine, Cardiovascular and Metabolic Disease Center, Inje University, Busan, 614-735, Korea.

Mol Cells ; 34(4): 357-65, 2012 Oct.

Article in En | MEDLINE | ID: mdl-23104437

Subject(s)

Antineoplastic Agents/pharmacology; Gene Expression Regulation, Neoplastic/drug effects; Mitochondrial Turnover/genetics; Naphthols/pharmacology; Resorcinols/pharmacology; Stilbenes/metabolism; Antineoplastic Agents/chemistry; Caspases/metabolism; Cell Survival/drug effects; Cell Survival/genetics; Down-Regulation/drug effects; Down-Regulation/genetics; Drug Screening Assays, Antitumor; Humans; MCF-7 Cells; Membrane Potential, Mitochondrial/drug effects; Mitochondrial Proteins/genetics; Mitochondrial Proteins/metabolism; Mitochondrial Turnover/drug effects; Naphthols/chemistry; Oxidative Phosphorylation/drug effects; Resorcinols/chemistry; Resveratrol; Stilbenes/chemistry

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Resorcinols / Stilbenes / Gene Expression Regulation, Neoplastic / Mitochondrial Turnover / Naphthols / Antineoplastic Agents Limits: Humans Language: En Journal: Mol Cells Journal subject: BIOLOGIA MOLECULAR Year: 2012 Document type: Article Country of publication:

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