PKCÎ´-mediated phosphorylation of BAG3 at Ser187 site induces epithelial-mesenchymal transition and enhances invasiveness in thyroid cancer FRO cells.

Li, N; Du, Z-X; Zong, Z-H; Liu, B-Q; Li, C; Zhang, Q; Wang, H-Q

Li, N; Du, Z-X; Zong, Z-H; Liu, B-Q; Li, C; Zhang, Q; Wang, H-Q.

Affiliation

Li N; 1] Department of Biochemistry and Molecular Biology, China Medical University, Shenyang, China [2] Key Laboratory of Cell Biology, Ministry of Public Health and Key Laboratory of Medical Cell Biology, Ministry of Education, China Medical University, Shenyang, China.

Oncogene ; 32(38): 4539-48, 2013 Sep 19.

Article in En | MEDLINE | ID: mdl-23108398

Subject(s)

Adaptor Proteins, Signal Transducing/metabolism; Epithelial-Mesenchymal Transition; Protein Kinase C-delta/metabolism; Thyroid Neoplasms/metabolism; Thyroid Neoplasms/pathology; Adaptor Proteins, Signal Transducing/genetics; Animals; Apoptosis Regulatory Proteins; CHO Cells; Cell Line, Tumor; Cell Movement/genetics; Cricetulus; Epithelial-Mesenchymal Transition/genetics; Humans; Phosphorylation; Protein Binding; Protein Kinase C-delta/genetics; Serine/metabolism; Thyroid Neoplasms/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Neoplasms / Adaptor Proteins, Signal Transducing / Protein Kinase C-delta / Epithelial-Mesenchymal Transition Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 2013 Document type: Article Affiliation country: China

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