ER stress activates NF-&#954;B by integrating functions of basal IKK activity, IRE1 and PERK.

Tam, Arvin B; Mercado, Ellen L; Hoffmann, Alexander; Niwa, Maho

ER stress activates NF-κB by integrating functions of basal IKK activity, IRE1 and PERK.

Tam, Arvin B; Mercado, Ellen L; Hoffmann, Alexander; Niwa, Maho.

Affiliation

Tam AB; Division of Biological Sciences, Section of Molecular Biology, University of California, San Diego, La Jolla, California, United States of America.

PLoS One ; 7(10): e45078, 2012.

Article in En | MEDLINE | ID: mdl-23110043

Subject(s)

Endoplasmic Reticulum Stress/physiology; I-kappa B Kinase/metabolism; NF-kappa B/metabolism; Protein Serine-Threonine Kinases/metabolism; eIF-2 Kinase/metabolism; Animals; Blotting, Western; CHO Cells; Cell Line; Chromatin Immunoprecipitation; Cricetinae; Electrophoretic Mobility Shift Assay; Endoplasmic Reticulum Stress/genetics; Endoribonucleases/genetics; Endoribonucleases/metabolism; Humans; I-kappa B Kinase/genetics; Membrane Proteins/genetics; Membrane Proteins/metabolism; Mice; NF-kappa B/genetics; NIH 3T3 Cells; Protein Serine-Threonine Kinases/genetics; eIF-2 Kinase/genetics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: NF-kappa B / Protein Serine-Threonine Kinases / EIF-2 Kinase / I-kappa B Kinase / Endoplasmic Reticulum Stress Limits: Animals / Humans Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

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