Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.

Hurt, Julie K; Coleman, Jennifer L; Fitzpatrick, Brendan J; Taylor-Blake, Bonnie; Bridges, Arlene S; Vihko, Pirkko; Zylka, Mark J

Hurt, Julie K; Coleman, Jennifer L; Fitzpatrick, Brendan J; Taylor-Blake, Bonnie; Bridges, Arlene S; Vihko, Pirkko; Zylka, Mark J.

Affiliation

Hurt JK; Department of Cell and Molecular Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, United States of America.

PLoS One ; 7(10): e48562, 2012.

Article in En | MEDLINE | ID: mdl-23119057

Subject(s)

Analgesics/pharmacology; Protein Tyrosine Phosphatases/metabolism; Thiamine/analogs & derivatives; Thiamine/pharmacology; Acid Phosphatase; Administration, Oral; Analgesics/administration & dosage; Analgesics/pharmacokinetics; Animals; Ganglia, Spinal/drug effects; Ganglia, Spinal/enzymology; Male; Mice; Mice, Knockout; Neurons, Afferent/drug effects; Neurons, Afferent/enzymology; Phosphorylation; Protein Tyrosine Phosphatases/genetics; Spinal Cord/drug effects; Spinal Cord/enzymology; Substrate Specificity; Thiamine/administration & dosage; Thiamine/pharmacokinetics

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thiamine / Protein Tyrosine Phosphatases / Analgesics Limits: Animals Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States Country of publication: United States

Fulltext

Add to My VHL

XML

PubMed Links

Search on Google