ETV6-NTRK3 as a therapeutic target of small molecule inhibitor PKC412.

Chi, Hoang Thanh; Ly, Bui Thi Kim; Kano, Yasuhiko; Tojo, Arinobu; Watanabe, Toshiki; Sato, Yuko

Chi, Hoang Thanh; Ly, Bui Thi Kim; Kano, Yasuhiko; Tojo, Arinobu; Watanabe, Toshiki; Sato, Yuko.

Affiliation

Chi HT; Department of Medical Genome Sciences, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo 108-8639, Japan. kk086406@mgs.k.u-tokyo.ac.jp

Biochem Biophys Res Commun ; 429(1-2): 87-92, 2012 Dec 07.

Article in En | MEDLINE | ID: mdl-23131561

Subject(s)

Antineoplastic Agents/pharmacology; Oncogene Proteins, Fusion/antagonists & inhibitors; Protein Kinase Inhibitors/pharmacology; Staurosporine/analogs & derivatives; Antineoplastic Agents/therapeutic use; Apoptosis/drug effects; Cell Line, Tumor; Cell Proliferation/drug effects; Hematopoiesis/drug effects; Humans; Mitogen-Activated Protein Kinase Kinases/metabolism; Neoplasms/drug therapy; Neoplasms/enzymology; Phosphorylation/drug effects; Protein Kinase Inhibitors/therapeutic use; Proto-Oncogene Proteins c-akt/metabolism; STAT5 Transcription Factor/metabolism; Staurosporine/pharmacology; Staurosporine/therapeutic use

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Oncogene Proteins, Fusion / Staurosporine / Protein Kinase Inhibitors / Antineoplastic Agents Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2012 Document type: Article Affiliation country: Japan Country of publication: United States

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