Curcumin serves as a human kv1.3 blocker to inhibit effector memory T lymphocyte activities.

Lian, Yi-Tian; Yang, Xiao-Fang; Wang, Zhao-Hui; Yang, Yong; Yang, Ying; Shu, Yan-Wen; Cheng, Long-Xian; Liu, Kun

Lian, Yi-Tian; Yang, Xiao-Fang; Wang, Zhao-Hui; Yang, Yong; Yang, Ying; Shu, Yan-Wen; Cheng, Long-Xian; Liu, Kun.

Affiliation

Lian YT; Department of Cardiology, Union Hospital, Huazhong University of Science and Technology, Wuhan 430022, China.

Phytother Res ; 27(9): 1321-7, 2013 Sep.

Article in En | MEDLINE | ID: mdl-23132777

Subject(s)

Curcumin/pharmacology; Immunologic Memory/drug effects; Kv1.3 Potassium Channel/antagonists & inhibitors; T-Lymphocytes/immunology; Arthritis, Rheumatoid/immunology; Cell Proliferation/drug effects; Dose-Response Relationship, Immunologic; HEK293 Cells; Humans; Interferon-gamma/immunology; Multiple Sclerosis/immunology; T-Lymphocytes/drug effects

Key words

Kv1.3 channels; TEM cells; autoimmune disease; curcumin; human

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Curcumin / Kv1.3 Potassium Channel / Immunologic Memory Limits: Humans Language: En Journal: Phytother Res Journal subject: TERAPIAS COMPLEMENTARES Year: 2013 Document type: Article Affiliation country: China Country of publication: United kingdom

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