DUSP6/MKP3 is overexpressed in papillary and poorly differentiated thyroid carcinoma and contributes to neoplastic properties of thyroid cancer cells.

Degl'Innocenti, Debora; Romeo, Paola; Tarantino, Eva; Sensi, Marialuisa; Cassinelli, Giuliana; Catalano, Veronica; Lanzi, Cinzia; Perrone, Federica; Pilotti, Silvana; Seregni, Ettore; Pierotti, Marco A; Greco, Angela; Borrello, Maria Grazia

Degl'Innocenti, Debora; Romeo, Paola; Tarantino, Eva; Sensi, Marialuisa; Cassinelli, Giuliana; Catalano, Veronica; Lanzi, Cinzia; Perrone, Federica; Pilotti, Silvana; Seregni, Ettore; Pierotti, Marco A; Greco, Angela; Borrello, Maria Grazia.

Affiliation

Degl'Innocenti D; Molecular Mechanisms Unit, Department of Experimental Oncology and Molecular Medicine, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy.

Endocr Relat Cancer ; 20(1): 23-37, 2013 Feb.

Article in En | MEDLINE | ID: mdl-23132790

Subject(s)

Adenocarcinoma, Follicular/metabolism; Biomarkers, Tumor/genetics; Carcinoma, Papillary/metabolism; Cell Differentiation; Dual Specificity Phosphatase 6/metabolism; Thyroid Neoplasms/metabolism; Adenocarcinoma, Follicular/genetics; Adenocarcinoma, Follicular/pathology; Adult; Aged; Aged, 80 and over; Apoptosis; Biomarkers, Tumor/metabolism; Blotting, Western; Carcinoma, Papillary/genetics; Carcinoma, Papillary/pathology; Cell Adhesion; Cell Movement; Cell Proliferation; Cells, Cultured; Dual Specificity Phosphatase 6/genetics; Female; Gene Expression Profiling; Humans; Male; Middle Aged; Mitogen-Activated Protein Kinase 1/genetics; Mitogen-Activated Protein Kinase 1/metabolism; Mitogen-Activated Protein Kinase 3/genetics; Mitogen-Activated Protein Kinase 3/metabolism; Neoplasm Staging; Oligonucleotide Array Sequence Analysis; RNA, Messenger/genetics; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Thyroid Gland/cytology; Thyroid Gland/metabolism; Thyroid Neoplasms/genetics; Thyroid Neoplasms/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thyroid Neoplasms / Carcinoma, Papillary / Biomarkers, Tumor / Cell Differentiation / Adenocarcinoma, Follicular / Dual Specificity Phosphatase 6 Limits: Aged80 Language: En Journal: Endocr Relat Cancer Journal subject: ENDOCRINOLOGIA / NEOPLASIAS Year: 2013 Document type: Article Affiliation country: Italy Country of publication: United kingdom

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