Pregnancy induces transcriptional activation of the peripheral innate immune system and increases oxidative DNA damage among healthy third trimester pregnant women.

Jiang, Xinyin; Bar, Haim Y; Yan, Jian; West, Allyson A; Perry, Cydne A; Malysheva, Olga V; Devapatla, Srisatish; Pressman, Eva; Vermeylen, Francoise M; Wells, Martin T; Caudill, Marie A

Jiang, Xinyin; Bar, Haim Y; Yan, Jian; West, Allyson A; Perry, Cydne A; Malysheva, Olga V; Devapatla, Srisatish; Pressman, Eva; Vermeylen, Francoise M; Wells, Martin T; Caudill, Marie A.

Affiliation

Jiang X; Division of Nutritional Sciences, Cornell University, Ithaca, New York, United States of America.

PLoS One ; 7(11): e46736, 2012.

Article in En | MEDLINE | ID: mdl-23133592

Subject(s)

DNA Damage; Immunity, Innate; Transcriptional Activation; Adult; Case-Control Studies; Choline/metabolism; Cluster Analysis; Diet; Epigenomics; Female; Gene Expression Profiling; Gene Expression Regulation; Genome, Human; Genomics; Histones/metabolism; Humans; Interleukin-6/biosynthesis; Leukocytes/metabolism; Leukocytes, Mononuclear/cytology; Oligonucleotide Array Sequence Analysis/methods; Oxidative Stress; Pregnancy; Pregnancy Trimester, Third; Tumor Necrosis Factor-alpha/biosynthesis

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Damage / Transcriptional Activation / Immunity, Innate Type of study: Clinical_trials / Observational_studies / Risk_factors_studies Limits: Adult / Female / Humans / Pregnancy Language: En Journal: PLoS One Journal subject: CIENCIA / MEDICINA Year: 2012 Document type: Article Affiliation country: United States

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