Development of doxorubicin-induced chronic cardiotoxicity in the B6C3F1 mouse model.

Desai, Varsha G; Herman, Eugene H; Moland, Carrie L; Branham, William S; Lewis, Sherry M; Davis, Kelly J; George, Nysia I; Lee, Taewon; Kerr, Susan; Fuscoe, James C

Desai, Varsha G; Herman, Eugene H; Moland, Carrie L; Branham, William S; Lewis, Sherry M; Davis, Kelly J; George, Nysia I; Lee, Taewon; Kerr, Susan; Fuscoe, James C.

Affiliation

Desai VG; Personalized Medicine Branch, Division of Systems Biology, National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR 72079, USA. varsha.desai@fda.hhs.gov

Toxicol Appl Pharmacol ; 266(1): 109-21, 2013 Jan 01.

Article in En | MEDLINE | ID: mdl-23142469

Subject(s)

Cardiotoxins/toxicity; Disease Models, Animal; Doxorubicin/toxicity; Heart Diseases/chemically induced; Animals; Body Weight/drug effects; Body Weight/physiology; Chronic Disease; Crosses, Genetic; Dose-Response Relationship, Drug; Heart/drug effects; Heart/physiology; Heart Diseases/blood; Heart Diseases/pathology; Male; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Organ Size/drug effects; Organ Size/physiology; Species Specificity

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Doxorubicin / Disease Models, Animal / Cardiotoxins / Heart Diseases Type of study: Prognostic_studies Limits: Animals Language: En Journal: Toxicol Appl Pharmacol Year: 2013 Document type: Article Affiliation country: United States Country of publication: United States

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